List of drugs for the treatment of arthrosis of the knee
Osteoarthritis of the knee joint( gonarthrosis) is a complex disease that is not always treatable. Therefore, in this article, we have prepared for you a list of drugs that are most effective in treating this disease.
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1st group of drugs: anti-inflammatory drugs
What is the danger of NSAID administration?
2nd group of agents: chondroprotectors
What is important to remember when treating chondroprotectors?
Drugs for intra-articular injection
Warning: All information on remedies for arthrosis of the knee joint is published exclusively for informational purposes for personal review. Do not try to use them yourself without consulting a doctor: self-medication can cause irreparable harm to your health!
All medicines for the treatment of knee osteoarthritis can be divided into several large groups by the mechanism of action.
1st group: anti-inflammatory drugs
Aertal - one of the new drugs for gonarthrosis
It is with non-steroidal anti-inflammatory drugs( NSAIDs) that the treatment of osteoarthritis of the knee usually begins.
This group of drugs includes such drugs as aspirin( acetylsalicylic acid), phenylbutazone, etodolac, indomethacin, sulindac, ibuprofen, piroxicam, aceclofenac, tenoxicam, diclofenac, lornoxicam, naproxen, rofecoxib, ketoprofen, meloxicam, nabumetone, tiaprofenic acid, nimesulide, flurbiprofen, celecoxib and others.
NSAIDs differ in both the strength of the action and the likelihood of developing side effects.
These drugs do not contain anti-inflammatory hormones, but nevertheless in most cases are able to cope well with joint pains and reduce inflammation in them.
Thus, the greatest analgesic effect is usually possessed by ketoprofen, diclofenac, indomethacin, while aspirin, ibuprofen, amidopyrin relieve pain significantly worse. But since many people can have individual reactions to different medications, then the effectiveness of these drugs may differ significantly from the generally accepted norms - both in one and the other direction.
It is generally believed that the greatest anti-inflammatory effect is available for such drugs as indomethacin, diclofenac, flurbiprofen, and ibuprofen, aspirin and naproxen, on the contrary, are able to reduce inflammation worse.
Side effects of
Unfortunately, despite the fact that non-steroidal anti-inflammatory drugs usually help to effectively relieve pain in osteoarthritis and other diseases, they are not very safe for health and have quite strong side effects. That's why doctors usually appoint them not very long courses and whenever possible in small doses.
What is the danger of NSAID administration?
a) problems from the gastrointestinal tract, primarily - effects on the gastric mucosa
NSAIDs cause side effects from the stomach
The intake of NSAIDs dramatically increases the likelihood of erosion and even ulcers of the gastric mucosa. This is especially true of people who had previously( or at the moment) such diseases as gastritis and peptic ulcer of the stomach and duodenum, as well as elderly patients.
However, in recent years, NSAIDs of the new generation have been synthesized, in which the negative effect on the gastrointestinal tract is significantly reduced.
This group of drugs are called selective inhibitors of COX-2, and include agents such as nimesulide and celecoxib.
b) Side effects from the kidneys
NSAIDs reduce the rate of renal blood flow, and also contribute to the retention of water and sodium in the body, which can increase blood pressure, as well as the development of acute heart failure and kidney failure.
c) Heart and blood vessel problems
Non-steroidal anti-inflammatory drugs, among other things, affect the blood coagulation system. If they are not properly taken, patients may develop blood vessel thromboses and even stroke or myocardial infarction. To medicines for which such an effect is characteristic, first of all those same COX-2 inhibitors, which reduce the risk of developing gastric complications, are included.
Things to remember when taking NSAIDs
As you can see, non-steroid drugs are not nearly as harmless as it is commonly believed. That is why you should not prescribe yourself such treatment, but you need to see a doctor who will choose the drug that is right for you and its dose.If it is necessary to take painkillers for arthrosis of the knee joint for a long time, it is better to use drugs of other groups for this, which, if taken for a long time, do not give such harmful side effects and have a large selective effect, without adversely affecting gastric, renal or cardiovascular diseases,cardiovascular system.
For these purposes, preparations like Movalis are more suitable, which can be taken in long courses - from several weeks to several months and more - but, of course, also only under the supervision of a doctor.
In addition, the intake of NSAIDs is fraught with the fact that it "obscures" the symptoms of arthrosis: as you know, pain is a signal from the body that something is wrong in it. If the pain is completely removed by the reception of these medicines, the likelihood is that a person with such a disease will wave a hand on the disease, relax and will not do anything for recovery, except for taking pain medications.
This approach is very dangerous, because despite the absence of pain, the disease continues to progress, the cartilaginous tissue is still destroyed, and a person can think that everything is in order with health and there is nothing to worry about.
In fact, the correct approach to taking NSAIDs should be as follows: it is necessary to take these medicines as prescribed by the doctor, but not to forget about the disease, but in order to create an opportunity without joint pain to undergo a comprehensive treatment: take other medications,which are necessary for the treatment of osteoarthritis, undergo the necessary physiotherapeutic procedures, massage courses and other medical measures that could not be carried out in the presence of pain.
The second group of agents: chondroprotectors
chondroprotectors are the most important drugs for arthrosis of joints.
Chondroprotectors( CP) are drugs that promote the protection of cartilaginous tissue and enhance its formation( synthesis) in the joints.
Unlike anti-inflammatory drugs, HP not only remove the symptoms of arthrosis of the knee joint, but also affect the very cause of osteoarthritis - they contribute to the improvement of cartilage tissue nutrition and its recovery. In this sense, chondroprotectors are one of the most important medicines for the treatment of this disease.
This group of agents includes such active ingredients as chondroitin sulfate and glucosamine. They can, in various combinations, be a part of various medications - such as Dona, Terafrex, Arthra, Structum, Chondroxide, Elbona, Chondroitin Akos, Chondrolon, Zinaxin, Arthrin and others.
Arthra is a combined preparation containing equally and glucosamine, and chondroitin sulfate( 500 mg each in one capsule).The drug is produced by the American company Unifarm, the cost of one of its packages, depending on the number of capsules, costs from 500 to 1,700 rubles. Arthra is considered one of the best chondroprotectors at the moment.
This medication is also combined: one capsule contains 500 mg of glucosamine and 400 mg of chondroitin sulfate, and is manufactured by the German company Bayer. Take teraflex, depending on the stage of the disease, 2-3 capsules per day. It is worth, depending on the number of tablets, from 600 rubles( for packing 30 capsules) to 1500( 120 capsules) and above.
Don contains only glucosamine. Produced by Don in the form of sachets( bags with powders for oral administration), capsules, as well as ampoules for intramuscular injection. For the most effective treatment, manufacturers recommend combining it inside with intramuscular injections.
This medicine is manufactured by Rottapharm( Rottapharm) and its price ranges from 1000 to 1300 rubles - both for capsules and sachets, and for ampoules.
This is a mono-drug of chondroitin sulfate, which is manufactured by the Russian pharmaceutical company Microgen. It is produced as a dry substance in ampoules for dilution and subsequent intramuscular administration.
One ampoule, which must be diluted in 1 ml of water, contains 100 mg of active substance. Enter chondrolone for 1 or 2( with good tolerability) of the ampoule every other day by a course of 25-30 injections. Its price at the beginning of 2013 is from 1000 to 1200 rubles per package of 10 ampoules.
Structum is also a mono-drug that contains chondroitin sulfate in an amount of 250 and 500 mg. Produced by Pierre Fabre Medicaments Productions( France).
It is prescribed in a dose of 1000 mg per day, i.e. It is necessary to take 2 capsules a day for 500 mg or four - about 250 mg. Packing with 60 capsules of this chondroprotector will cost you 1200-1300 rubles.
Elbona is a Russian remedy, which includes only glucosamine sulfate. This drug is produced in 2 ml ampoules( plus 1 ml ampoule with a solvent) for intramuscular injection;one ampoule contains 400 mg of active ingredient.
As seen from the name, this CP is also a mono-drug containing chondroitin sulfate in an amount of 250 mg of active ingredient in one capsule. This medicine, as well as the previous one, is produced in Russia.
ointment chondroxide for joints
This medication contains only one active ingredient - chondroitin sulfate, but is produced not only in the form of capsules( 250 mg each) but also as a 5% ointment. It is produced by the Russian pharmaceutical company Nizhpharm.
For the therapeutic effect, the dose of this drug, like other members of this group, should be 1000 mg of active ingredient per day, i.e.4 capsules per day.
Packing of 60 capsules will cost 400-500 rubles. Ointment in a 30 gram tube will cost from 250 to 300 rubles() .
What is important for a patient to remember when treating chondroprotectors?
- primarily, chondroprotective medications are time-consuming drugs. This means that the effect of treatment develops very slowly, and it can be seen only after 3-5 months, and the course of treatment with these drugs is from 6 to 12 months and sometimes more;please be patient.
- CP only work in the early stages of arthrosis - at 1 and 2 degrees;at 3 degrees of this disease, chondroprotectors do not make sense anymore, because on it the entire cartilaginous tissue of the joint is already destroyed and there is simply nothing to restore.
- among doctors now there is no general opinion about whether it is worth taking glucosamine and chondroitin sulfate together or separately. There are studies that suggest that with the joint administration of these two substances they can weaken each other's action. But while this question remains open, it is better to leave it at the discretion of your attending physician and, if possible, give preference to the products of large, reliable pharmaceutical companies with high quality products.
Medications for intra-articular injection( injections inside the joint)
In addition to drugs administered internally and intramuscularly, a large therapeutic effect in osteoarthritis gives the introduction of various drugs directly into the joint cavity( intraarticular injections).Thanks to this method of administration, the drugs directly fall directly into the area of action-into the synovial fluid through which the cartilaginous tissue is fed.
Most often, corticosteroid anti-inflammatory hormones are used to inject the joint: hydrocortisone, kenalog, celeston, diprospan, flosteron, and others. These drugs are injected into the joint, because when taken in tablets such medications give very many side effects. But when injected directly into the joint, they very quickly and effectively reduce pain and inflammation in the joint, facilitating the patient's condition.
Important point: corticosteroids, like NSAID preparations, do not treat osteoarthritis, but only have anti-inflammatory and analgesic effect. In order to really treat this disease, you need to use other drugs - the same chondroprotectors.
Also in recent years, such a method of treatment as intraarticular administration of hyaluronic acid( sodium hyaluronate) has been used. This tool acts on the joint as a "liquid prosthesis" or an additional synovial fluid that seems to create a protective layer in the joint that improves movement in the joint, helps to reduce the trauma of the joint during movements, moisturizes the cartilaginous tissue and improves its nutrition.
Sodium hyaluronate is available in the form of preparations such as fermatron, duralan, ostenil, synviscus. The therapeutic effect of the administration of these medications is usually very good, but, unfortunately, not everyone can afford this treatment.
So, one dose of a fermatron for intra-articular administration will cost 3500-4000 rubles, while the curative rate is 3-4 injections 1 time per week in each diseased joint. Therefore, a large price is the only factor that hinders the development of this method of treatment.
A good therapeutic effect for gonarthrosis is provided by various medications used locally.
So, such ointments as Fastum-gel, indomethacin and butadion ointments, Menovazine, Voltaren-gel, Nikoflex-cream, Espol, diclofenac-ointment, and many others have shown themselves as therapeutic ointments and gels for topical application.
They have a good curative effect, but it is important to remember that only 4 to 8% of the drug substance passes through the skin to the "destination" - the patient's joint; therefore, anti-inflammatory and analgesic treatment with ointments, creams and gels is almost always necessary with drugs, taken orally or intramuscularly.
Various medicinal substances for external use can be used for the preparation of medical compresses. These include, for example, bischofite( an oil derivative that has a beneficial effect on arthrosis), dimexide( an anti-inflammatory and analgesic medicine that penetrates well through the skin), as well as a medical bile that has good warming and absorbing properties.
However, in order to control such a complex disease as arthrosis of the knee joints, sometimes it is not enough to just take drugs in one form or another.
Drug treatment should be combined with physiotherapy procedures for arthrosis of joints, sanatorium treatment, and if your doctor does not object, you can use effective folk recipes for treatment of gonarthrosis.
And remember: for effective therapy of arthrosis of the knee joint, it is dangerous to engage in self-medication. If you have joint pain, consult a doctor!
What drugs are used to treat arthrosis of the knee joint?
What is arthrosis of the knee joint?
Osteoarthritis of the knee joint( or, as it is also called, gonarthrosis) is a disease of the knee joint, accompanied by pains, impaired motor functions and deformation of the cartilage cartilage of the knee joints. Usually it appears in people of an age prone to fattening - and women suffer from gonarthrosis more often than men. It is accepted to divide this disease on a stage, each of which intensifies and complicates the coping and treatment of the disease.
Osteoarthritis of the knee joint, treatment and preparations for which it is necessary to select with the mind is a disease, a frequent problem now, especially in the elderly. The first stage of arthrosis of the knee joints is almost not detected by ordinary residents, since the pain is episodic, not particularly strong, joint deformities do not occur. It can last very long - from several months to several years in a row. Usually, pains persecute people after the beginning of active activity, in the process of heavy physical labor and some time after it, after which they disappear to the following significant loads.
Sometimes this is accompanied by a so-called Baker's cyst - an abnormal accumulation of articular fluid in the back of the knee. She usually descends after taking a course of anti-inflammatory drugs - to operate Baker's cyst in any case is not worth it, since it is not associated with cancer.
The second stage is much heavier. The pains appear at the beginning of walking, the joints begin to crack painfully and click, the leg with difficulties bends at an angle of less than 90 degrees. A person with the second stage of gonarthrosis becomes difficult to get up on his feet, many types of physical activity become inaccessible: the pains become too strong. Abnormal accumulation of articular fluid manifests itself in more than half the cases. There is an initial deformation of the osseous cartilaginous tissues of the knee joints, they are "flattened", becoming wider.Osteoarthrosis
The third stage is the most severe for a patient with gonarthrosis. Pain in the knees does not recede for a minute, even at rest it is difficult to find a position in which it would become tolerable. The knee can not be bent at an angle of less than 90 degrees and it is very painful to straighten the leg completely. The bones and cartilages of the knee joint are subject to noticeable erosion, and physical loads are simply impossible. This is truly the end of a healthy human life.
How to deal with arthrosis of the knee joints and is there any means to treat it?
The first thing you need to remember a person who showed signs of at least the first stage of gonarthrosis is to consult a specialist in the nearest hospital. It is necessary to avoid excessive loads on the affected joints, to lose excess weight to facilitate walking and functioning of the lower extremities. Also, knee joint injuries should not be tolerated - they significantly increase the risk of arthrosis symptoms.
If you are already exposed to later stages of this unpleasant illness, then it must be treated. Fortunately, this is possible.
First of all, under the strict supervision of your doctor, you need to buy NSAIDs( non-steroidal anti-inflammatory drugs for arthrosis).They will stop the spread of excess articular fluid, remove possible edema and reduce pain when working joints. It should be remembered that this is only the beginning of treatment, the removal of only some of the symptoms, and not the very cause of gonarthrosis. Do not be deceived - it is still very far from the true cure.
It is also necessary to take chondroprotektorov - drugs that help the body to repair damaged cartilage tissue and eliminate the effects of joint deformation. Unfortunately, they work slowly and can not be cured for a cure - at the third stage of arthrosis, when the cartilage is subjected to almost total entropy, these drugs will be powerless. However, the less that chondroprotectors can do is to stop the patient's condition, restore minor cartilage damage and normalize the production of articular fluid, restoring the necessary lubricating properties( which, of course, will prevent further deterioration of knee joints).Ointments help to relieve pain
Do not forget about the presence of ointments and creams from pain in the joints and muscles. They, although they do not have any curative effect, quite well restore the circulatory system( especially - warming ointments), which contributes to the early restoration of the joint and the rehabilitation of the surrounding muscles. In general, treatment of gonarthrosis with ointments helps patients to relieve pain in the knees and accelerate the recovery process - this should not be discounted, limited only to chondroprotectors and NSAIDs.
Like ointments, compresses are also used. Experts in this matter advise them much more than warming ointments: the effect of using compresses is similar, but much stronger and versatile. Of these medicines, medical bile, bischofite and dimexide are especially prominent.We recommend reading: Osteoarthritis of the knee joint of the 1st degree
All these agents not only produce an external warming effect, but they are also able to soak through the skin, acting directly on the disease center from the inside( unlike the advertised gels and ointments of all colors,external warming effect).When using any medicine, be sure to consult a specialist who is treating you.
Also have the right to life intraarticular injections. They differ in their types and uses and have the greatest number of restrictions to use and contraindications. Many modern doctors make the grossest mistakes in the use of these drugs, which is quite unfortunate for the patients.
The injections do not work at once - between injections it is necessary to take a break in the area of two weeks, and no more than five injections into one joint for a course of treatment. Hormonal injections relieve inflammatory processes without producing any other positive effects. Preparations with arthrosis on hyaluronic acid envelop the damaged joint surfaces, preventing further erosion of bone-cartilaginous tissues. Unfortunately, for all its high efficiency, hyaluronic injections are very expensive;The treatment course will cost you no less than a thousand dollars. However, this is one of the most effective methods of treatment of gonarthrosis without surgical intervention.
Do not forget about manual therapy of knee joints. When treating the initial stages of arthrosis of the knee joints, it has a truly miraculous effect. Already after a small number of procedures, the overwhelming majority of patients feel tremendous relief and improvement of the situation with the diseased knees. Experienced specialists of manual therapy raised to their feet a huge number of patients with gonarthrosis, which otherwise were subject to surgery.
Remember the benefits of using exercises of therapeutic gymnastics and the use of walk sticks in everyday life. Exercise individually, according to your situation and stage of the disease, after consulting with an experienced doctor. The walking stick should be chosen taking into account the distance from the floor to the wrist of your hand, stretched down. A cane is worn in the hand opposite the leg with a diseased knee joint( say, the left leg is susceptible to gonarthrosis, and in the right you wear a cane).At each step on a sick leg, transfer your center of gravity to the cane: this helps to reduce the load when walking.
What does this have to endure?
It is necessary to understand the danger of diseases of the knee joints, including arthrosis. Preparations for the treatment of joint arthrosis should be chosen carefully, taking into account all the nuances. At the first signs of pain in the knees, try to find an experienced doctor who can give you the correct and effective instructions for the prevention of this problem. Remember: in the initial stages of gonarthrosis is much more treatable than late. If you want to live your life without pain and unnecessary complications, keep an eye on your health and the health of your knees.
Treatment of diseases of the knee jointDiseases of the musculoskeletal system - one of the most common. Diseases of knee joints are divided into post-traumatic, inflammatory and dystrophic. Post-traumatic diseases occur after injuries or bruises, resulting in a violation of metabolic processes both inside the joint itself and in the surrounding tissues.
Diseases of knee joints of an inflammatory nature occur as a result of infections in various organs of a person. An infection with blood or lymph flow penetrates into the surrounding tissue of the tissue either into the joint itself, hitting it. Dystrophic diseases occur against the background of hereditary pathologies or as a result of metabolic disorders due to chronic diseases or aging of the human body.
Inflammatory diseases of the knees
The group of inflammatory joint diseases leads arthritis as the most common disease. This group includes bursitis, periarthritis and a number of less well-known diseases. Arthritis is a disease of one( monoarthritis) or several joints( polyarthritis), which occurs as a result of inflammatory processes in the human body. Arthritis of the knee joint( chasing) appears after systemic diseases of the human body, the infection from which penetrates into tissues in the region of the knee joint or directly into it.
Arthritis can occur as a result of a malfunction of the immune system or external non-traumatic effects that disrupt the regeneration processes in the knee tissues.
A patient with arthritis experiences severe pain due to depletion of the cartilaginous connective tissue and bone trauma
Arthritis without treatment goes into chronic forms, for example, in rheumatoid arthritis, arthrosis and other diseases of a dystrophic nature. Bursitis affects the periarticular bag, which has a branched network of blood vessels. Infection is brought into her by a current of blood from infected organs. Periarthritis - an inflammation of the tendon in the area of attachment of the thigh muscles to the tibia, the knee joint itself is not inflamed.
Dystrophic diseases of knee joints
Arthrosis is a degeneration of cartilage and surrounding tissues of the knee joint. With arthrosis cartilaginous tissue in it exfoliates and ceases to function as a shock absorber when loaded on it. With age, tissue regeneration processes slow down or completely stop. Arthrosis is subject to hard physical labor, athletes and representatives of some professions experiencing large static loads on the legs( sellers, hairdressers, etc.).
Tendonitis is an inflammation of the articular ligaments. This disease is also called the "jumper's knee", as it often develops in athletes and jumpers on the jogging leg when the knee jumps out. As a result of regular overloads in the tissues of the tendon and cartilage, necrosis of some of their areas is formed. Progressive increase in tissue necrosis is called tendonosis.
Chondromatosis is a disease of an unknown nature, as a result of which cartilaginous nodes of various diameters are formed in the synovial membrane of the periarticular bag.
Their number varies from one to several tens. These nodes can be attached to the bag or be in it, freely moving( articular mouse).The disease is accompanied by pain, a crunch in the knees and a restriction of mobility.
Treatment of inflammatory diseases of knee joints
How is arthritis treated? For the treatment of the knee joint with arthritis, it is necessary to establish the type of infections and the focus of its spread, so the doctor suggests the patient to conduct a survey for the search for an infectious organ. At the same time, local anti-inflammatory drugs and pain medications are prescribed( only after the examination).
Once the infection is identified, the doctor determines how to treat the knee joints. He prescribes specific antibiotics to eliminate infection. In the early stages of this method of treatment gives good results. Chronic arthritis requires the use of potent drugs that are injected directly into the knee. They can be anti-inflammatory, hormonal agents and chondroprotectors.
What should be the treatment for bursitis? To treat the knees with bursitis should be complex, starting with bed rest and applying cold compressors to the inflamed area. Inflammation of the periarticular bag is associated with an increase in her synovial fluid. Analysis of this fluid gives an answer about the nature of the disease and allows the doctor to prescribe medications for treatment.
Inflammation of synovial shoulder bag leads to effusion of fluid there
If the disease is contagious, antibiotics are prescribed. To remove swelling apply punctures synovial fluid, which reduces the pain of the patient. It is useful to use physiotherapeutic procedures, but not during the period of exacerbation of the disease.
What should I do to treat periarthritis? With periarthritis of the knee joint, treatment should be carried out in the same way as with arthritis. Curing periarthritis is possible, since the joint is not inflamed and its structure is not disturbed.
Treatment of arthritis and periarthritis is aimed at relieving inflammation and increasing metabolism in the tissues of the joint and adjacent muscles.
Treatment of diseases of a dystrophic nature
What is knee joint treatment for arthrosis? Osteoarthritis is characterized by progressive destruction of cartilage, and the main task is to stop this process and promote active regeneration of cartilaginous tissue. But, since arthrosis causes severe pain in the patient, first prescribe analgesics and anti-inflammatory drugs. Regeneration of cartilaginous tissue is achieved by the adoption of chondroprotectors - preparations of natural origin, produced from cartilage of animals and shells of crustaceans.
The use of corticosteroids in the form of injections in the treatment of arthrosis is recommended in exceptional cases to relieve acute pain. These drugs give serious complications and are not recommended by doctors of many countries. In this situation, only the doctor decides what to treat.
What is the treatment for tendonitis? At an early stage of the disease, if inflammation of the knee tendon is detected, it is important to ensure peace and apply cold compresses to the inflamed area. Further treatment of knee joints should be handled by a doctor who prescribes anti-inflammatory drugs and injections of painkillers. Only in case of rupture of ligaments, operative measures are prescribed.
Attention should also be paid to the treatment of chondromatosis. For the treatment of joints with chondromatosis, therapy is not applied. Only surgery is indicated.
In diseases of knee joints, self-medication should be avoided, which in most cases leads to irreversible consequences, disability and immobility of the patient.
Treatment of arthritis of the knee joint - medications
Such knee joint disease as arthritis not only worsens the quality of life, causing permanent disturbances of motor activity, but also reduces its duration. Therefore, it is very important to correctly develop a therapeutic scheme that will slow the progression of pathology and support the regenerative processes in tissues. The main medicamental treatment of arthritis of the knee joint is drugs designed to stop the inflammatory process, pain syndrome, as well as the restoration of an erased cartilaginous tissue.
What are the medicines to treat arthritis of the knee joint?
A classic set of drugs for conservative therapy of the disease in question includes agents from the following groups:
- anti-inflammatory non-steroidal series;
- basic anti-inflammatory drugs( immunosuppressors);
- biological products;
- pain relievers;
- additional medication.
Let's consider more in detail each type of drugs.
Effective anti-inflammatory drugs for arthritis and arthrosis of the knees
The following names are used from non-steroid medications:
The main component of knee arthritis therapy is considered basic anti-inflammatory drugs:
- Arava( Leflunomide);
Glucocorticosteroids for the treatment of arthritis and arthrosis
The described group of medications can be used systemically and locally, locally.
In the first case, the drug of choice is Prednisolone in low dosages.
For periarticular and intraarticular injections, the following are used:
Biological medicines in the treatment of rheumatoid arthritis as a new trend in the treatment of joint diseases It is important to clarify that the type of medicines in question has nothing to do with dietary supplements. Biological preparations carry out a purposeful blocking of the main causes of inflammation, their name is due to the use of biotechnology in the production process.
It is recommended to use the following names for such products:
In Russia there are only 2 medicines from this group - Remicade( based on infliximab) and Mabter( based on rituximab).
Drugs-chondroprotectors for knee arthritis
The means for restoring cartilaginous tissue are available in various dosage forms.
Oral( powders, tablets, capsules):
- Fortart Fortress;
- Chondroitin Ultra;
- Chondroitin Akos;
Injections for intramuscular injections:
Solutions for intraarticular administration:
- : Ostanenyl;
- hyaluronic acid.
What pain medications are used to treat arthritis of the knee joint?
For the relief of pain in medical practice, it is recommended to use both non-narcotic analgesics and opiates. Most often choose such names of drugs:
- Paracetamol with Codeine;
- Morphine( rare).
Additional medicines for the treatment of arthritis and arthrosis
As supporting and symptomatic therapy it is advisable to take the following types of medications:
- amino acids;
Their choice is carried out individually according to the needs of the patient.
Knee joint arthrosis
The traditional treatment for arthrosis of the knee joint is based on the intake of various medications, the purpose of which is to reduce pain in the patient, as well as the restoration of damaged cartilage tissue. In this article, we would like to consider popular drugs for arthrosis of the knee, which are usually prescribed by the doctor when diagnosed as "gonarthrosis."
Immediately we want to note that the drugs described below are very serious and should be appointed directly by the attending physician. Self-medication in many cases can lead to very undesirable consequences.
Knee arthrosis medications are divided into several groups, among which are topical medications in tablets, injections, medications in the form of ointments and compresses, as well as intraarticular injections.
The first group of drugs for gonarthrosis: anti-inflammatory drugs
The beginning of the treatment of arthrosis of the knee usually occurs with the appointment of non-steroidal anti-inflammatory drugs, among which are Piroxicam, Indomethacin, Diclofenac, Flexen, Ibuprofen.
These preparations for arthrosis of the knee joint are usually administered with severe inflammation accompanied by synovitis. They relieve pain and reduce the development of inflammatory processes, but they do not treat the disease itself.
Such medications for knee arthrosis should be prescribed by a physician and should not be taken longer than 2-3 months. Otherwise, you risk getting side effects from prolonged use.
The second group of drugs for gonarthrosis: chondroprotectors
A more effective group of drugs are the chondroprotectors Chondroitin sulfate and Glucosamine, the action of which is directed to the restoration of cartilaginous tissue. Take such medications with arthrosis of the knee joint is recommended together. Only with complex use they help to restore the damaged joint surface and to increase the production of joint lubrication.
However, we should not exaggerate the possibilities of this group of drugs, because they are useless in the third stage of arthrosis, when the cartilage is almost destroyed. However, even in the case of earlier stages of the disease, chondroprotectors act slowly and need to be taken regularly during several courses of treatment.
Usually recommend a 40-day course of taking these drugs every 6 months for 3-5 years. In any case, taking such medications from time to time will not bring positive results.
The third group of drugs: vascular preparations
Along with this, with arthrosis of the knee, vasodilators are prescribed, among which, for example, Trental, Xaninol Nicotinate. These drugs for knee arthrosis help restore blood circulation and relieve spasms of small vessels of the legs. Such drugs are indicated for taking with the chondroprotectors
. The fourth group of drugs: painkillers
As a local anesthetic for arthrosis, it is recommended to apply various ointments and compresses. It is recommended warming ointments Menovazine, Nikoflex, as well as ointments that have anti-inflammatory properties-Fastum, Voltaren-gel, etc. Dimexide is an effective remedy for swelling of joints and inflammations. However, you should use this remedy cautiously, as it is in many cases allergic and causes burns.
To get a quick relief, intraarticular injections of corticosteroid hormones are sometimes prescribed, among them Kenalog, Betamethasone, Hydrocortisone. However, such injections are useless with pronounced bone deformities.
To repair damaged joint tissues, intraarticular injections of chondroprotectors are used Arteparon, Control. Usually, a 5-7 injection course of this treatment is recommended.
One of the rather new methods is intra-articular injection of hyaluronic acid, which is a "lubricant" for the joint. However, the effectiveness of this method justifies its high cost only in the first stage of gonarthrosis.
Knee joint arthrosis tablets
Knee joint injuries are difficult to tolerate due to high soreness and limited mobility, and are difficult to treat. This disease, like arthrosis, requires an integrated approach to therapy, which includes oral administration of drugs and topical treatment in the form of applications, compresses and ointment application.
Tablets from arthrosis of the knee joint are divided into several groups and affect various manifestations of the disease:
All of them are especially effective at the initial stages of the disease, require admission courses and strict compliance with the prescription of a specialist.
Anti-inflammatory tableted medicines
Currently, non-steroidal anti-inflammatory drugs, such as Indomethacin, Ibuprofen, Diclofenac, Piroxicam and many others are most often used. Their main advantage is that, unlike hormonal drugs, non-steroidal preparations have far fewer contraindications and side effects.
All these drugs are divided into two large groups: inhibitors of cyclooxygenase of the first and second type. Preparations of the second group have fewer side effects and are better tolerated by the gastrointestinal tract, nevertheless they can have a serious negative effect on the cardiovascular system, kidneys and liver, as well as on the digestive tract in people with increased sensitivity to these substances. Allergic reactions are possible, these drugs are contraindicated for pregnant and lactating mothers.
The second type of cyclooxygenase inhibitors( for example, the drug Movalis) are better perceived by patients and have a pronounced anti-inflammatory and analgesic effect. With the correct admission of courses with compliance with dosage and under the supervision of a doctor, swelling, inflammation, pain and sensation of swollen hot knee go away. Much better mobility of the joint and a person gets the opportunity to move independently, giving up the cane or even crutches.
Analgesics for knee arthrosis
The removal of pain in arthrosis can significantly improve the patient's condition, because in most cases it is the increased sensitiveness and soreness of the knee that interferes with a full life, reduces efficiency and mobility. Most of the non-steroid drugs along with anti-inflammatory drugs have a pronounced analgesic effect, which allows reducing the number of medications used. The usual analgesics in tablets are not always able to reduce pain in the bones and joints, which makes their intake irrational. Most often, the doctor prescribes various ointments, compresses and applications with drugs like Dimexide to remove the edema and reduce pain. Recently, injections directly into the knee joint have been widely used. The course of such injections helps to improve health, restore mobility of the joint. Such drugs are prescribed solely by the attending physician depending on the severity of the illness.
Means for maintaining the vascular tone
When the joints are damaged their nutrition, therefore, the use of vasodilator drugs helps to improve blood supply to the affected area. Such measures contribute to the improvement of tissues and the restoration of their functions. In the vast majority of cases, vasodilators are used in conjunction with substances called chondroprotectors. They help to restore the affected cartilage of the knee joint, and the means that expand the vessels, contribute to increased blood supply.
Among the often prescribed medications are Trental and Xantinol Nicotinat, which relieve spastic manifestations and help the work of blood vessels and capillaries.
Chondroprotectors - effective remedy for cartilage restoration with arthrosis
If the cartilage is not completely worn, there is hope to influence its condition and try to restore its density and functionality. For this purpose, substances called hodoprotectors are used.
There are two main drugs - chondroitin sulfate and glucosamine. Both are effective in the defeat of cartilaginous tissue, so they are most often used together or even as part of a single drug. Recently, the composition of such tablets began to add hyaluronic acid, which helps to restore the natural "lubrication" of the knee joint. In addition to the addition of chondroprotective agents, hyaluronic acid is used in the form of injections directly into the joint.
Preparations Chondroitin and Glucosamine are well tolerated and have no side effects, moreover, they help improve the condition of hair, skin and nails. To obtain a pronounced effect, it is necessary to take them for a long time in courses, under the supervision of the attending physician. Interruption of admission or short irregular courses, as well as reception with very damaged articular cartilage, will not give the desired result. Chondroprotectors act slowly, but have a pronounced therapeutic effect in the initial stages of arthrosis of the knee, especially when using complex therapy in combination with other effective drugs, compresses and injections.
Self-medication even with "harmless" chondroprotectors can lead to serious consequences, so consult a doctor and follow only his instructions. The sooner the treatment is started, the better the result and the more chances to keep strong, healthy and mobile joints.